Summary
A British Medical Journal has given U.S. health regulators some documents that it says show the makers of Prozac knew of problems with the drug as far back as the 1980's. The publication says Eli Lilly & Co. produced internal memos noting the drug showed several "troubling side effects" – including suicidal behavior – during clinical trials.
Original source:
http://www.usatoday.com/news/health/2004-12-31-prozac-risks_x.htm
Details
- A British medical journal said Friday that it had given U.S. regulators confidential drug company documents suggesting a link between the popular anti-depressant Prozac and a heightened risk of suicide attempts and violence.
- The journal said the documents, reportedly missing for a decade, had formed part of a 1994 lawsuit against Eli Lilly on behalf of victims of a workplace shooting in Louisville The gunman who killed eight people and himself in 1989, Joseph Wesbecker, had been prescribed Prozac a month before the shootings.
- The journal said one of the records, dated November 1988, reported that fluoxetine, the generic name for Prozac, had caused "behavioral disturbances" in clinical trials.
- The journal said it had turned the documents over to the U.S. Food and Drug Administration, which had agreed to review them.
- The journal said the office of Congressman Maurice Hinchey, D-N.Y., also was examining the documents to determine whether Eli Lilly had withheld data from the public and the FDA.
- "This is an alarming study that should have been shared with the public and the FDA from the get-go, not 16 years later," Hinchey was quoted as saying.
- In a statement to the journal, Eli Lilly said Prozac "has helped to significantly improve millions of lives."
- "It is one of the most studied drugs in the history of medicine and has been prescribed for more than 50 million people worldwide.
- The safety and efficacy of Prozac is well studied, well documented and well established."
- In October, FDA ordered that all antidepressants carry warnings that they "increase the risk of suicidal thinking and behavior" in children.
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